Myotonic muscular dystrophy is a common multi-system disorder that affects the skeletal muscles the muscles that move the limbs and trunk as well as smooth muscles the muscles that control the digestive system and cardiac muscles of the heart.
The two types of myotonic dystrophy are caused by mutations in different genes. There are two variations of myotonic dystrophy type 1: the mild and congenital types. Mild myotonic dystrophy is apparent in mid to late adulthood. Affected individuals typically have mild myotonia and cataracts. Congenital myotonic dystrophy is often apparent at birth.
Congenital myotonic dystrophy has only been seen in Type 1 myotonic dystrophy and not in Type 2. Myotonic dystrophy is the most common form of muscular dystrophy that begins in adulthood. It affects about 1 in 8,000 people worldwide. Type 1 myotonic dystrophy is the most common form in most countries.
Myotonic dystrophy type 1 (DM1) was first described over a century ago. DM1 is caused by expansion of a CTG triplet repeat in the 3' non-coding region of DMPK, the gene encoding the DM protein kinase. More recently a second form of the disease, myotonic dystrophy type 2 (DM2) was recognized, which results from repeat expansion in a different gene.
What is myotonic dystrophy? Myotonic dystrophy is the most common type of muscular dystrophy that begins in adult age, the expert said. “It is part of a group of inherited disorders called muscular dystrophies. It is usually characterized by continuous muscle wasting and weakness.”
media.punditarena.com - 2022 DISCLAIMER: All models on www.xxxcrowlimg.com adult site are 18 years or older. media.punditarena.com has a zero-tolerance policy against ILLEGAL pornography. All galleries and links are provided by 3rd parties. We have no control over the content of these pages. We take no responsibility for the content on any website which we link to, please use your own discretion while surfing the porn links.