Since it was first published by Chance and colleagues [4,12], this value of 1–2% of respiration going to O 2 •− has propagated through the literature and has been used erroneously to estimate mitochondrial O 2 •− production in vivo, even though the original authors made it clear that it only applied to particular experimental conditions .
Parkes R. Rate of respiration: the forgotten vital sign. Emergency Nurse. 2011;19(2):12-7. Rodriguez-Molinero A, Narvaiza L, Ruiz J, Galvez-Barron C. Normal respiratory rate and peripheral blood oxygen saturation in the elderly population. Journal of the American Geriatric Society. 2013. 61(12):2238-40. doi:10.1111/jgs.12580
Shortness of breath (SOB), also medically known as dyspnea or dyspnoea (), is an uncomfortable feeling of not being able to breathe well enough. The American Thoracic Society defines it as a subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity, and recommends evaluating dyspnea by assessing the intensity of it's distinct.
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