We perform high-throughput fragment screening, kinetics and affinity determination, binding specificity profiling and antibody characterization, etc.
SPR, All Acronyms, viewed April 25, 2022, MLA All Acronyms.
SPR binding assa ys are widely used in drug discovery, from fragment screening through analyte ranking and in-depth kinetic characterization.
A purity of 90% or more is recommended.
There will be a live streaming component which will include the three plenary sessions and the two presidential addresses.
The flow then switches to the running buffer, and the dissociation of the analyte from the target is monitored.
While the on-rates are similar for the MTA- and SAH-bound conditions, the off-rates are approximately 100X slower.
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Reaction Biology provides project-tailored solutions to assure the highest chance of success in biomolecular interaction research using SPR services by using a broad biophysics knowledge base and excellent instrument coverage.
High-information content Combining kinetic information with affinity and potency data early in the drug discovery process ensures that promising compounds are not being discarded.
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